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22.07.2017
The optimal laboratory chair for genetic engineering
Genetic engineering | laboratory chair
Complex questions, conclusive answers
The Polymerase Chain Reaction (PCR) is used as the basis for medical diagnostics. In this procedure DNA is exponentially amplified in many duplication steps within a very short space of time. The PCR basically consists of a constantly repeated cycle of three reaction steps. As complex as the biological processes in genetic engineering are, the question of what qualities a suitable laboratory (and thus a laboratory chair) should have is not as difficult.
It is very simple: No contamination in the genetic engineering laboratory
The most important condition for the error-free implementation of a Polymerase Chain Reaction is unambiguous and easily understood: No contamination! As every type of DNA in the sample to be examined is reproduced, it is essential to prevent contact with undesired foreign material. Owing to exceptionally high sensitivity to external influences, there are special requirements in genetic engineering laboratories where PCR is performed. The individual steps take place in structurally separated areas: in a Pre-PCR area and a Post-PCR area. The materials and equipment used should also be separated. For example, a separate set of pipettes, filter tip boxes and disposable containers for each work area is obligatory. The route to the Pre-PCR area for equipment which was used for a Post-PCR process is blocked. In order to guarantee optimal cleanliness, all objects and surfaces used must always be in perfect and hygienic condition - before and after the work. The cleaning is effected using preferably a sodium hypochlorite decontamination solution.Structure and hygiene - How the right laboratory chair reduces the risk
The strict requirements for genetic engineering laboratories also have effects on the requirements of the workplace chairs used. A laboratory chair can contribute to the required hygienic conditions in numerous ways. It must be washable and resistant to all common decontamination solutions. It has a design that is as seamless as possible so that there are no joints and cracks where unnoticed residues can build up. A laboratory chair can also be a valuable aid when it comes to structured processes. If the chair can be clearly assigned to a defined work area, e.g. with an attached label, this can prevent it being unintentionally moved between different areas and thus becoming a contamination risk in genetic engineering laboratories. 1
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